Screening for Colorectal Cancer in Average and High Risk Population

• Status: Completed
• Trial end date: 2017-10-30
• Target enrollment: 0
• Participant gender: All

Summary

The existing evidence from epidemiological studies and randomized controlled trials has consistently assures the cost effectiveness and the influential role of screening in reducing incidence rates and deaths caused by Colorectal Cancer (CRC). Population based organized screening programmes, which should be considered an obligation that is not to be postponed, require valuable information that can be reliably extrapolated from well-designed pilot study conducted prior to programme implementation.

The main objectives of the current pilot CRC screening project, named after "Al-Kindy College of Medicine", was to evaluate and explore the specific aspects of the intended population-based organized CRC screening programme, including: barriers affecting adherence to the programme, performance indicators of the proposed screening programme, the target population in which CRC screening is a legitimate healthcare priority, quality assurance of screening tests and colonoscopy services, and to propose an algorithm that will provide a clinically and logistically acceptable positivity rate.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Lewai Sharki Abdulaziz, MSc PhD
• Collaborators: Al-Kindy College of Medicine; Research & Development Directorate, Ministry of Higher Education, Iraq
• Treatments: Bisacodyl; Calcium Channel Blockers; Diltiazem; Lidocaine; Nitroglycerin; Picosulfate sodium; Tribenoside

Criteria

Inclusion Criteria:

• residents of Baghdad city

• being ≥45 years of age with stop age of 80 years.

Exclusion Criteria:

• history of inflammatory bowel disease (IBD).

• colonoscopy (CS)/flexible sigmoidoscopy (FS)/ double contrast barium enema (DCBE) performed within the last year.

• persistent altered bowel habits.

• chronic abdominal pain.

• visible bleeding per rectum.

• long term use of anticoagulant.