Overview

Selective Neoadjuvant Treatment According to Immunohistochemical Subtype for HER2 Negative Breast Cancer Patients

Status:
Completed
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
This is an open-label study that includes two substudies of random distribution. First,a sample of the primary tumor will be obtained and will be analyzed by an immunohistochemical technique to determine several markers.Depending on the expression of these markers, the patients will be characterize as group 1 (Luminal A phenotype) or group 2 (Basal phenotype) and a random assignment will be performed to standard or experimental treatment.
Phase:
Phase 2
Details
Lead Sponsor:
Spanish Breast Cancer Research Group
Collaborator:
Pfizer
Treatments:
Carboplatin
Cyclophosphamide
Docetaxel
Epirubicin
Exemestane
Goserelin