Overview

Sensitivity of New Exercise Tests in Chronic Obstructive Pulmonary Disease (COPD)

Status:
Completed

Trial end date:
2010-06-01

Target enrollment:
0

Participant gender:
All

Summary

This study was designed to test the following hypothesis: The 3-min constant rate step test and the 3-min constant rate shuttle walk test will be sensitive to detect improvement in exertional dyspnea following acute bronchodilation in patients with COPD.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Laval University

Collaborators:

Boehringer Ingelheim
McGill University

Treatments:

Bromides
Ipratropium

Criteria

Inclusion Criteria:

- age > 50 years

- smoking history > 10 packs/year

- post-bronchodilator FEV1 between 30 and 80% predicted and FEV1/FVC < 70% as assessed
in previous pulmonary function test (GOLD stage II and III)

Exclusion Criteria:

- respiratory exacerbation within the preceding 2 months

- history of asthma

- significant O2 desaturation (SaO2 < 85%) at rest or during exercise

- presence of another pathology that could influence exercise tolerance