Overview

Sequential/Combination Therapy in Nucleoside or Nucleotide Analogue (NA)-Suppressed Chronic Hepatitis B Patients

Status:
Unknown status
Trial end date:
2019-12-31
Target enrollment:
Participant gender:
Summary
The aim of the prospective study is to determine whether combination/ sequential therapy with Entecavir, Peginterferon alfa-2b and immunomodulators Granulocyte Macrophage Colony Stimulating Factor (GMCSF)+vaccine could induce HBsAg loss in chronic hepatitis B patients with maintained Hepatitis B Virus (HBV) DNA suppression on long-term nucleoside or nucleotide analogue (NA).
Phase:
Phase 4
Details
Lead Sponsor:
Qin Ning
Treatments:
Entecavir
Interferon-alpha
Molgramostim
Peginterferon alfa-2b
Sargramostim
Vaccines