Sequential High-Dose Chemotherapy and Stem Cell Transplantation in Treating Patients With Chemotherapy-Sensitive Metastatic Breast Cancer

• Status: Completed
• Trial end date: 2000-12-01

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may kill more tumor cells.

PURPOSE: Phase II trial to study the effectiveness of sequential high-dose chemotherapy followed by peripheral stem cell transplantation in treating patients with metastatic breast cancer that is responding to chemotherapy.

• Phase: Phase 2

Details

• Lead Sponsor: Yale University
• Treatments: Cyclophosphamide; Megestrol; Megestrol Acetate; Melphalan; Tamoxifen; Thiotepa