Sequential Therapy Versus Quadruple Therapy as Second Line Treatment After Failure of the Standard Triple Therapy for H Pylori Infection

• Status: Completed
• Trial end date: 2014-12-01

Summary

The aim of this study is to evaluate the efficacy of sequential therapy, i.e. 5 days of PPI + amoxicillin followed by 5 days of PPI + two antimicrobial drugs( clarithromycin and tinidazole ) versus quadruple drug regimen( i.e.-14 days of PPI+ bismuth + metronidazole + tetracycline ) as second line treatment of H. pylori .

• Phase: Phase 3

Details

• Lead Sponsor: Soroka University Medical Center
• Treatments: Amoxicillin; Bismuth; Bismuth subsalicylate; Clarithromycin; Dexlansoprazole; Lansoprazole; Metronidazole; Tetracycline; Tinidazole