Sequential Use of Propofol/Midazolam and Dexmedetomidine for Sedation in Mechenical Ventialtion Patients in ICU.
Status:
Unknown status
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
For the patient who passed the screen of weaning from ventilation, the traditional sedation
drug such as propofol and midazolam should be decreased or stopped, then it would induce the
stress response and agitation, such as hypertension,tachycardia etc. In order to resolve that
problem, the sedation should be given again. but if renewed to sedation, it would cause
prolonged sedation and ventilation duration.
So as to resolve above issues, after the patient passed the screen of weaning, sedation is
changed to Dexmedetomidine, a new sedation drug, that could wake up at any time. So our study
to compare the efficacy and safety of sequential sedation of propofol or midazolam and
dexmedetomidine in mechanical ventilated ICU patients.