Serotonin Effect in Functional Dyspepsia

• Status: Completed
• Trial end date: 2007-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate whether Efexor (venlafaxine) is effective in the treatment of functional dyspepsia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Radboud University
• Treatments: Serotonin; Serotonin Agents; Venlafaxine Hydrochloride

Criteria

Inclusion Criteria:

• Persistent upper gastrointestinal symptoms;

• Absence of any serious organic cause of the complaints at previous upper gastrointestinal endoscopy (including gastric ulcer, carcinoma, oesophageal reflux disease, portal hypertension, hernia hiatus >2 cm or severe gastritis);

• Over 18 years of age;

• Written informed consent.

Exclusion Criteria:

• History of bipolar disorder;

• Contra-indication for venlafaxine;

• Current or planned pregnancy or lactation;

• Diagnosed alcoholism, anorexia nervosa or bulimia;

• Current or recent (within the last two weeks) use of a selective serotonin re-uptake inhibitor (SSRI) or MAO-inhibitor;

• Any other condition or circumstance that, in the opinion of the investigator or the physician, would compromise the subject's successful participation in this trial.