Serotonin and Motor Plasticity

• Status: Unknown status
• Trial end date: 2017-11-30
• Target enrollment: 0
• Participant gender: Female

Summary

With this study, the investigators aim to test whether acute administration of selective serotonin reuptake inhibitors (SSRI) improves motor performance in a sequential motor learning task in comparison to placebo in healthy humans.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Max Planck Institute for Human Cognitive and Brain Sciences
• Collaborator: University of Leipzig
• Treatments: Citalopram; Dexetimide

Criteria

Inclusion Criteria:

• female

• right-handed

• healthy

• has taken oral contraceptives (ovulation inhibitor) continuously for at least 3 months

• has read and agreed to study parameters

Exclusion Criteria:

• tattoos on head or neck

• non-removable metal on or in body

• alcohol abuse

• is currently taking medication

• smokes more than 3 cigarettes per day

• positive drug test

• pregnancy

• plays an instrument professionally

• plays videogames more than 2 hours per week

• is a professional athlete

• suffers from migraines

• has taken part in another study, where motor learning skills and/or medication is a factor, in the last 3 months

• heart rhythm disorders (long QT)

• hypertension

• calcium or magnesium deficiency

• neurological disorders

• chronic metabolic disorders

• liver or kidney diseases

• immunodeficiency

• endocrine disorders

• psychiatric disorders

• tumors

• injuries to the head and brain