Serratus Plane Block With Parenteral Opioid Analgesia Versus Patient Controlled Analgesia in Rib Fractures

• Status: Not yet recruiting
• Trial end date: 2020-03-01
• Target enrollment: 58
• Participant gender: All

Summary

In this multicentre randomised controlled trial, adult patients with isolated chest trauma and two or more unilateral rib fractures will be randomised to either serratus plane block and patient controlled analgesia or patient controlled analgesia alone. Our primary outcome is the static visual analogue scale score at one hour.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chelsea and Westminster NHS Foundation Trust
• Collaborator: St George's University Hospitals NHS Foundation Trust
• Treatments: Morphine

Criteria

Inclusion Criteria:

• 18 years of age or older

• Isolated chest trauma

• Two or more unilateral rib fractures

Exclusion Criteria:

• Bilateral rib fractures

• Clavicular fractures

• Polytrauma

• Sternal fracture or injury

• Thoracic spine injury

• Decreased Glasgow Coma Scale score

• Dementia

• Delirium or psychiatric illness

• Chronic lung disease

• Coagulopathy

• End stage liver disease

• Significant renal failure, defined as a creatinine >150µmol/l

• Local infection at potential site of SBP insertion

• Pregnancy or breastfeeding

• History of chronic pain or opioid dependence

• Current chronic analgesic therapy

• Requirement for tracheal intubation and mechanical ventilation

• Allergy to local anaesthetics and/or opioids

• Inability to control and self-administer opioids with PCA due to confusion, learning difficulties or poor manual dexterity

• Unable to speak and/or understand English