Serum Progesterone on the Day of Thawed Embryo Transfer and Pregnancy Rate After an Artificial Endometrial Preparation

• Status: Recruiting
• Trial end date: 2023-02-15
• Target enrollment: 0
• Participant gender: Female

Summary

To determine if different serum Progesterone levels on FET day are associated with different clinical pregnancy rates (CPR), and if increasing dosage of vaginal Progesterone in cases of lower serum Progesterone level on FET day can be either beneficial or detrimental regarding the CPR.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hillel Yaffe Medical Center
• Treatments: Progesterone

Criteria

Inclusion Criteria:

• women between age 18-38 undergoing FET in AC

• with body mass index (BMI) < 35 kg/m2

• a triple layer endometrium >6.5 mm after exogenous estrogen administration

• 1-2 good quality day 3 or 5 FET.

Exclusion Criteria:

• women with recurrent pregnancy losses (e.g. 2 abortions beyond 12th week or 3 abortions before 12th week)

• recurrent implantation failure (e.g. unsuccessful implantation of ≥4 good quality embryos)

• severe male factor (sperm concentration <5 million/ml), or presence of hydrosalpinx.