Overview

Serum Serotonin and Pruritus After Intrathecal Morphine in Cesarean Section

Status:
Completed
Trial end date:
2016-09-21
Target enrollment:
0
Participant gender:
Female
Summary
Pruritus is the commonest side effect of intrathecal morphine especially in parturient, but the exact mechanism of pruritus is not clear. Many mechanisms have been suggested. Among these mechanisms is the activation of the 5-HT3 receptors by the intrathecally injected morphine.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Assiut University
Treatments:
Morphine
Serotonin
Criteria
Inclusion Criteria:

- ASA I - II term pregnant patients scheduled for elective cesarean section

Exclusion Criteria:

- patients with a known allergy to the study drugs

- significant cardiac, respiratory, renal, neurological, or hepatic disease;
-coagulation disorders

- BMI > 30 kg/m2

- any itchy skin diseases.