Serum Tryptase Concentration During General Anaesthesia With Rocuronium

• Status: Completed
• Trial end date: 2014-05-15
• Target enrollment: 0
• Participant gender: Female

Summary

Rocuronium is a aminosteroid structured, non-depolarizing neuromuscular blocking agents (NMB). Epidemiological data presents that the frequency of hypersensitivity reactions caused by rocuronium have been increased. Determinations of serum tryptase concentrations are interdisciplinary recommended in diagnosis of its adverse reactions. No studies have been performed to explain specific role of rocuronium doses on serum tryptase values. The aim of this study was to investigate the potential effect of rocuronium on serum tryptase concentrations.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Bialystok
• Treatments: Anesthetics; Rocuronium

Criteria

Inclusion Criteria:

• ASA 1-2, no allergy and perioperative hypersensitivity reactions during anaesthesia

Exclusion Criteria:

• steroid therapy, allergy in medical history, mastocytosis