Sevoflurane Versus Intravenous Anaesthetic Agents in Morbid Obese Patients

• Status: Unknown status
• Trial end date: 2011-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this prospective randomized clinical study was to compare anesthesia, in morbidly obese patents (BMI >50) who underwent BPD-RYGBP with either sevoflurane or propofol with remifentanyl.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Patras
• Treatments: Anesthetics; Propofol; Remifentanil; Sevoflurane; Succinylcholine

Criteria

Inclusion Criteria:

• Age 18-50 yrs

• BMI>50 kg/m2

• Written consent for the participation in the study

Exclusion Criteria:

• History of significant cardiac disease, (aortic stenosis, angina, CHF or previous cardiac or intrathoracic operations)

• Significant renal dysfunction (serum creatinine>1.8 mg/dl)

• Significant liver dysfunction (evidenced by abnormal LFTs)

• History of hyper or hypothyroidism

• History of psychiatric or neurologic disorders

• Recall during general anesthesia

• Substance abuse (alcohol or other drugs)

• Counter-indications of placement of thoracic epidural catheter( previous spine surgery or coagulation abnormalities )

• Refusal to participate in the study