Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity
Status:
Recruiting
Trial end date:
2025-06-30
Target enrollment:
Participant gender:
Summary
Patients with sleep apnea are at increased risk of developing cardiovascular disease - with
women at potentially greater risk than men. Contributing mechanisms are not well understood,
but may be related to how women respond to low oxygen and, given over 70% of patients with
sleep apnea are obese, the impact of obesity. This project seeks to increase our
understanding of mechanisms that may contribute to sex differences in the cardiovascular
response to low oxygen with the hope that this knowledge will improve the efficacy of current
therapies and support the discovery of novel therapeutics.