Shivering Prevention During Cesarean Section by Intrathecal Injection of Magnesium Sulfate

• Status: Completed
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Shivering is a common post-anesthetic complication occurring in up to 65% of patients undergoing spinal or epidural anesthesia. Shivering may interfere with electrocardiogram, blood pressure and oxygen saturation monitoring. In addition, shivering increases oxygen consumption, carbon dioxide production and metabolic rate by up to 400%. Thus, it may result in problems in patients with low cardiac and pulmonary reserves. Preventing shivering could therefore result in better postoperative outcomes or reduce the incidence of post-surgical complications.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Bupivacaine; Magnesium Sulfate

Criteria

Inclusion Criteria:

1. Age 18 to 35years.

2. Undergo elective cesarean section under spinal anesthesia.

3. ASA physical status I-II.

4. Singleton pregnancy.

5. At least 38 weeks gestation.

Exclusion Criteria:

1. Women with history of cardiac, liver or kidney diseases.

2. Women with allergy to amide local anesthetics or medication included in the study.

3. Women with any neurological problem.

4. Any contraindication of regional anesthesia.

5. Failed or insatisfactory spinal block.

6. Preoperative temperature more than 38⁰ C.