Short Against Long Antibiotic Therapy for Infected Orthopedic Sites
Status:
Not yet recruiting
Trial end date:
2025-09-30
Target enrollment:
Participant gender:
Summary
We will perform two concomitant RCTs, depending on the presence of infected osteosynthesis
material at enrolment:
- SALATIO 1. Infected implant not removed (or new material inserted): Randomization 6 vs. 12
weeks (+/- 5 days) of total antibiotic therapy counted since the first debridement for
infection. Early switch to oral targeted therapy.
- SALATIO 2. Infected implant without residual material (definitive removal or within the
interval of a two-stage exchange): Randomization 3 vs. 6 weeks (+/- 5 days) of total
antibiotic therapy counted since the first debridement for infection. Early switch to oral
targeted therapy.