Overview

Short-Course Anti-tuberculosis Regimens for Mild Spinal Tuberculosis

Status:
NOT_YET_RECRUITING
Trial end date:
2029-12-31
Target enrollment:
Participant gender:
Summary
To evaluate the non-inferiority in efficacy between the rifapentine- and moxifloxacin-containing short-course regimens (with rifampicin replaced by rifapentine and ethambutol replaced by moxifloxacin, while isoniazid and pyrazinamide remaining the same as the empirical regimen) and the empirical long-course regimen, so as to determine whether it is possible to shorten the treatment duration to 26 weeks for patients with mild spinal tuberculosis.
Phase:
PHASE2
Details
Lead Sponsor:
Shandong University
Collaborator:
Shandong Public Health Clinical Center
Treatments:
Ethambutol
Isoniazid
Moxifloxacin
Pyrazinamide
Rifampin
rifapentine