Short-Course Chemoradiotherapy Followed by Chemotherapy for the Treatment of Resectable Gastric Adenocarcinoma
Status:
Recruiting
Trial end date:
2027-12-31
Target enrollment:
Participant gender:
Summary
This phase Ib trial investigates the side effects and how well a shorter course of
chemotherapy and radiation treatment (chemoradiotherapy) for 2 weeks instead of 5 weeks
followed by standard chemotherapy works in treating patients with gastric cancer who are
scheduled to have treatment and then surgery to remove the tumor. Chemotherapy drugs, such as
capecitabine and fluorouracil, work in different ways to stop the growth of tumor cells,
either by killing the cells, by stopping them from dividing, or by stopping them from
spreading. Radiation therapy uses high energy sources to kill tumor cells and shrink tumors.
Giving short-course chemo-radiotherapy before chemotherapy and surgery may help to control
the disease.