Overview

Short-term Presurgical Study to Assess Molecular Predictors of Lapatinib's Effects in Primary Breast Cancer

Status:
Completed
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
To provide an in vivo measure of the activity of lapatinib. To assess the antiproliferative effects of lapatinib in breast cancer, ie how much lapatinib slows down the growth of cancer cells by measuring K167 (a marker of proliferation) in breast tumours before and after a short treatment with lapatinib.
Phase:
Phase 2
Details
Lead Sponsor:
Institute of Cancer Research, United Kingdom
Collaborator:
GlaxoSmithKline
Treatments:
Lapatinib