Overview

Sildenafil After the Fontan Operation

Status:
Completed
Trial end date:
2009-07-01
Target enrollment:
Participant gender:
Summary
In this study, the investigators will evaluate the effect of sildenafil on exercise tolerance in patients with a single cardiac ventricle who have undergone the Fontan operation. The investigators will also evaluate echocardiographic measures of ventricular function and measure quality of life changes using two validated quality of life measures. The hypothesis is that sildenafil will result in increased exercise tolerance in patients who have had the Fontan operation as compared to placebo.
Phase:
Phase 2
Details
Lead Sponsor:
Children's Hospital of Philadelphia
Collaborator:
The Mark H. and Blanche M. Harrington Foundation
Treatments:
Sildenafil Citrate