Sildenafil for Post-capillary Pulmonary Hypertension in Patients Undergoing Cardiac Surgery
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
Pulmonary hypertension increases the perioperative risk in patients undergoing cardiac
surgery for valvular heart diseases, especially in patients with a long life mitral valve
disease. The present study wants to test the hypothesis that intravenous administration of
sildenafil reduces pulmonary vascular resistances and afterload of the right ventricle.