Silodosin, Tadalafil Alone vs. Silodosin Plus Tadalafil as MET for Lower Ureteric Stones

• Status: Not yet recruiting
• Trial end date: 2023-09-30
• Target enrollment: 0
• Participant gender: All

Summary

This study will compare the efficacy of silodosin, tadalafil versus silodosin plus tadalafil as Medical Expulsive Therapy (MET) for lower ureteric stones.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Benha University
• Treatments: Silodosin; Tadalafil

Criteria

Inclusion Criteria:

• 168 patients aged >18 years old.

• Both sexes.

• Diagnosed with lower ureteric stone from 5mm to 10mm in size.

Exclusion Criteria:

• Patients with multiple or bilateral ureteric stones

• single kidney or impairment of renal function

• Urinary tract infection (UTI)

• Marked hydronephrosis

• Patients presenting with severe intractable pain and requiring emergency intervention

• Any urologic anomalies or history of ureteral surgery

• Pregnancy

• Pediatric populations

• Ischemic heart disease

• Congestive cardiac failure

• Complicated hypertension

• Patients on concomitant treatment with nitrates or calcium channel blockers.