Simplified Algorithm for the Prevention of Postoperative Nausea and Vomiting in an Oncological Hospital

• Status: Completed
• Trial end date: 2021-03-20
• Target enrollment: 0
• Participant gender: All

Summary

Previous history of nausea and vomiting induced by prior chemotherapy still not included as predictive factor of postoperative nausea and vomiting, although has been demonstrated that has influence in postoperative outcome.

The project aims to evaluate the efficacy of a simplified algorithm in prevention postoperative nausea and vomiting , with pacients with previous history of nausea and vomiting induced by prior chemotherapy, submitted to medium or large surgery.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Instituto do Cancer do Estado de São Paulo
• Treatments: Droperidol

Criteria

Inclusion Criteria:

• All patients who underwent medium to large surgery

Exclusion Criteria:

• Patients who are unable to communicate (orotracheal intubation after the surgery, confusion or agitation) or understand the Portuguese language;

• Insulin dependent patients

• Patients who underwent emergency surgery and neurosurgery

• Pacients who had an increased QT interval on the electrocardiogram

• History of allergy to dexametasone, ondansetron or droperidol

• Refusal to participate