Overview

Simplified Selective Digestive Tract Decontamination for the Prevention of Intensive Care Unit Acquired Infections

Status:
Unknown status

Trial end date:
2015-07-01

Target enrollment:

Participant gender:

Summary

A simplified graded gut decontamination protocol combined with rigorous bi-weekly screening and appropriate bacterial prophylaxis, will lead to a 25% reduction in the acquisition of blood stream infections and to a 25% reduction in lower airway colonization with multi drug resistant organisms. There will be no concomitant rise in gram-positive or fungal infection or a surgency of new resistance patterns.

Phase:

Phase 2/Phase 3

Details

Lead Sponsor:

Rambam Health Care Campus

Treatments:

Colistin
Neomycin
Nystatin
Vancomycin