Simvastatin Around Immediate Implant

• Status: Completed
• Trial end date: 2016-05-03
• Target enrollment: 0
• Participant gender: All

Summary

The study evaluated the effect of local application of simvastatin around immediate implant on the amount of gap fill, ridge dimensional alterations and bone density in humans.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ain Shams University
• Treatments: Simvastatin

Criteria

Inclusion Criteria:

• Patients between 20 and 50 years old

• requiring the extraction of 2 non-restorable maxillary canine or premolar on each side of the arch

• following extraction, the crestal bone had to be located 3 mm apical to the free gingival margin

• at least 3 mm of bone beyond the root apex was required to guarantee implant primary stability

Exclusion Criteria:

• unstable systemic diseases precluding surgical procedures

• compromised general health conditions that would impair bone healing including present history of bone irradiation, patient on bisphosphonates therapy, antitumor chemotherapy

• pregnancy

• compromised healing conditions e.g. uncontrolled diabetes mellitus