Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis

• Status: Unknown status
• Trial end date: 2006-02-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will analyse the effect of simvastatin on endothelium dependent venodilation in chronic renal failure patients treated by peritoneal dialysis. The hypothesis is that patients will have a greater endothelium dependent venodilation after four months of simvastatin use.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Federal University of São Paulo
• Treatments: Simvastatin

Criteria

Inclusion Criteria:

• end stage renal failure

• peritoneal dialysis

• LDL cholesterol > 100mg/dL

• > 18 years and < 80 years

Exclusion Criteria:

• using statin or nitrate

• liver disease

• diabetes mellitus