Simvastatin in Uveitis

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The study evaluates anti-inflammatory effects and safety of simvastatin in non-infectious uveitis.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology
• Treatments: Simvastatin

Criteria

Inclusion Criteria:

• diagnosis of active non-infectious uveitis

Exclusion Criteria:

• serious liver or kidney disease

• increased transaminase levels of >1.5 ULN

• planned or active pregnancy

• use of fibrates, nicotinic acid, cyclosporine A, antifungal drugs, macrolide antibiotics, verapamil, and grapefruit juice (>1 L/day).