Single Bolus Dose of Ketodex Versus Ketofol For Prevention Of Emergence Agitation In Adults Undergoing Nasal Surgeries

• Status: Completed
• Trial end date: 2019-11-23
• Target enrollment: 0
• Participant gender: All

Summary

• emergence agitation is seen in around 68% after nasal surgeries. Agitated patients needs more staff and nurses to control their abnormal movement which leads to self extubation , removal of catheters and bruises in the extremities.

• Dexmedetomidine, ketamine, propofol intravenous infusion and other agents was used to prevent EA . Recently, ketodex is found to reduce the incidence and severity of EA .

• We aim to compare single bolus dose of Ketodex Versus Ketofol For Prevention Of emergence Agitation in adults undergoing nasal surgeries.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Zagazig University
• Treatments: Dexmedetomidine; Ketamine; Propofol

Criteria

Inclusion Criteria:

• Patient acceptance.

• Both gender.

• Age (21-60) years old.

• patient with Body Mass Index (BMI) (25-35kg/m²).

• American Society of Anesthesiologist (ASA) I / II

• Adult patient scheduled to elective nasal surgeries

Exclusion Criteria:

• - Patient with difficult airway (mallampati III,IV).

• Altered mental status (psychiatric and anxiety disorder).

• Post traumatic stress disorders.

• History of allergy to study drugs.

• Patient on sedative or hypnotic medication.

• Patients with chronic pain or on painkiller.

• Patients with severe hepatic or kidney impairment.

• Patients having a history of thyrotoxicosis, hypertension, cardiac , chest or neurological disease.

• Patient receiving B agonist.

• Pregnant or breast feeding female.