Single Dose Ciprofloxacin in the Treatment of Childhood Cholera:Randomized Controlled Clinical Trial
Status:
Completed
Trial end date:
2002-07-01
Target enrollment:
Participant gender:
Summary
The study will be conducted to compare the efficacy and safety of a single dose of
ciprofloxacin oral suspension 20 mg/kg with a 3-day course of erythromycin oral suspension
administered in a dose of 12.5 mg/kg every 6 hours (12 doses) in the treatment of children,
aged 2-15 years with clinically severe cholera due to V. cholerae O1 or O139.
We hypothesize that single dose ciprofloxacin would result in similar outcome in the
clinicalcurewith that of erythromycin given in multiple doses.
Phase:
Phase 3
Details
Lead Sponsor:
International Centre for Diarrhoeal Disease Research, Bangladesh