Single Dose of Furosemide to Improve Respiratory Distress in Moderate to Severe Bronchiolitis

• Status: Completed
• Trial end date: 2016-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess if administration of an early single dose of a diuretic (furosemide) to children with moderate to severe bronchiolitis can reduce extravascular lung water in an effort to reduce respiratory rate, retractions, intubations, and length of stay.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Northwell Health
• Treatments: Furosemide

Criteria

Inclusion Criteria:

• Diagnosis of Acute Bronchiolitis

• Admission required per Emergency Department Physician

Exclusion Criteria:

• No legal guardian present

• Sulfa allergy

• Patient currently on existing diuretic therapy

• Tracheostomy

• Mild respiratory distress (not requiring admission)

• Hypotension / Hemodynamic Instability (defined by age specific criteria at time of intervention)

• Supplemental Oxygen at home

• History of Dialysis / Renal Disease

• Those enrolled in another drug interventional study