Single Oral Dose of Dexamethasone Versus Five Days of Prednisone in Adult Asthma

• Status: Completed
• Trial end date: 2015-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This study seeks to compare the effectiveness of a single dose of oral dexamethasone versus 5 days of oral prednisone in the treatment of mild to moderate asthma exacerbations to prevent relapse with an unscheduled return visit to a health care provider for additional asthma treatment within 14 days. The investigators hypothesize that the two treatments will be equally effective in relapse prevention.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alameda County Medical Center
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Glucocorticoids; Prednisone

Criteria

Inclusion Criteria:

• Age 18-55yo

• History of asthma

• Requires > 1 albuterol nebulizer

• Valid phone number

Exclusion Criteria:

• declines participation

• Past allergic reaction to corticosteroids

• Use of Oral steroids in the last 2 weeks

• Pregnant

• History of COPD, pulmonary fibrosis, cystic fibrosis, or other chronic lung disease

• History of HIV

• History of CHF

• History of Diabetes mellitus

• Active chickenpox (varicella) or shingles (herpes zoster)

• Active TB

• Requires admission to the Hospital

• Requires immediate airway intervention