Single Session Of Antimicrobial Photodynamic Therapy Using Indocyanine Green

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

In recent years, there has been a growing interest in the use of dental lasers for treatment of periodontal diseases. Commercially available photodynamic therapy for periodontal diseases utilizes methylene blue as a photosensitizer. In this study, the effects of a novel photosensitizer dye, indocyanine green (ICG), as an adjunct to nonsurgical treatment of chronic periodontitis will be evaluated.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: SVS Institute of Dental Sciences
• Treatments: Anti-Infective Agents; Photosensitizing Agents

Criteria

Inclusion Criteria:

Patients who were diagnosed with chronic periodontitis having a clinical evidence of periodontal pocket of ≥5mm, in at least 4 sites in each of the 3 quadrants.

• Systemically healthy male & female patients within the age group of 35-55 years.

• No history of medications affecting the periodontium (antibiotics, immunosuppressive drugs, anti-inflammatory, anti-oxidants, antibiotic tooth paste, mouthwashes) or periodontal therapy in the past 24 weeks period leading to the study.

Materials & Methods 26

• Minimum of 5 teeth in each quadrant.

Exclusion Criteria:

Medically compromised patients.

• Patients who had received any antibiotic, periodontal or laser therapy during the past 24 weeks of base line examination.

• Patients using antibacterial mouth rinses or medicated tooth paste during the past 24 weeks.

• Patients with history of tobacco chewing, smoking and alcohol consumption.

• Pregnant women & lactating mothers.