Single-Shot With Dexmedetomidine Versus Continuous Ultrasound-guided Erector Spinae Plane Block for Postoperative Pain Control After Percutaneous Nephrolithotomy

• Status: Not yet recruiting
• Trial end date: 2021-12-29
• Target enrollment: 0
• Participant gender: All

Summary

The current study is designed to assess the efficacy of a single shot ESPB with Dexmedetomidineversus continuous ESPB in perioperative analgesia for PCNL. Both techniques are conducted for patients undergoing PCNL under GA.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University

Criteria

Inclusion Criteria:

• Adult patients of age (18-50), ASA physical status I or II undergoing unilateral percutaneous nephrolithotomy

Exclusion Criteria:

• - Body mass index greater than 35 kg/m2.

• Pregnancy.

• Unstable coronary artery disease, congestive heart failure, or arrhythmias.

• Baseline heart rate (HR) less than 60 beats/min or baseline systolic blood pressure less than 100 mmHg.

• Pre-existing neurological deficits or neuropathy.

• Significant psychiatric or cognitive conditions interfering with consent or assessment.

• Significant renal impairment (creatinine above 2 mg/dl)

• Severe bronchopulmonary disease, including chronic obstructive pulmonary disease and obstructive sleep apnea.

• Known contraindications to peripheral nerve block, including local skin infections, bleeding diathesis, and coagulopathy.

• Allergies to local anesthetics, dexmedetomidine, or any component of multimodal analgesia.