Single Versus Combined Antibiotic Therapy for Bacterial Peritonitis in CAPD Patients

• Status: Unknown status
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare the efficacy of single versus combined antibiotic therapy for bacterial peritonitis in CAPD patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chulalongkorn University
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cefazolin; Ceftazidime; Ciprofloxacin; Gentamicins

Criteria

Inclusion Criteria:

• age >/= 18 years old

• ESRD patients on continuous ambulatory peritoneal dialysis more than 4 weeks

• presence of symptom or sign of peritonitis

• presence of WBC >100cell/mm3 with PMN >50% in peritoneal dialysate or gram stain positive for gram positive or gram negative bacteria

Exclusion Criteria:

• presence of polymicrobial organism, non-fermentative gram negative organism, fungus, mycobacteria in peritoneal fluid or culture-negative

• peritonitis from the organisms that required combined antibiotic therapy according to ISPD guideline 2010

• hospital-acquired peritonitis

• presence of catheter-related infection

• history of peritonitis within 4 weeks

• currently taking antibiotic

• allergic to the antibiotic that used in the study(penicillin or cephalosporin or quinolone or aminoglycoside)