Single-Versus Multiple-dose Antimicrobial Prophylaxis for Peroral Endoscopic Myotomy in Achalasia
Status:
Recruiting
Trial end date:
2020-03-01
Target enrollment:
Participant gender:
Summary
Achalasia cardia is a primary oesophageal motility disorder of unknown etiology. Recently,
peroral endoscopic myotomy (POEM) has gained widespread acceptance as an effective treatment
modality for achalasia.
Major adverse events are uncommon with POEM. Since the operator works close to mediastinum
during the POEM procedure, there is a potential for infectious complications. Therefore,
intravenous antibiotics are universally used to prevent infection-related adverse events.
There is no fixed protocol or duration of antibiotics for the same.