Single and Multiple Ascending Dose Study of Aducanumab (BIIB037) in Japanese Participants With Alzheimer's Disease
Status:
Completed
Trial end date:
2016-12-09
Target enrollment:
Participant gender:
Summary
The primary objective of the study is to evaluate the safety and tolerability of single and
multiple intravenous (IV) infusions of Aducanumab in Japanese participants with mild to
moderate Alzheimer's Disease (AD). The secondary objectives of this study are as follows: To
evaluate the serum pharmacokinetics (PK) of Aducanumab after single and multiple intravenous
(IV) infusions of Aducanumab; To evaluate the effect of single and multiple IV infusions of
Aducanumab on immunogenicity.