Single-dose Pharmacokinetics and Safety of Oral Lofexidine in Renally-Impaired Subjects
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
This is a phase 1, open-label, parallel-group, single-dose study of lofexidine in 8 adult
subjects with ESRD maintained on hemodialysis (3 times per week) and 8 control subjects with
normal renal function, recruited as 1:1 matches to each ESRD subjects, matched for gender,
age, and BMI.