Sirolimus Associated With Tacrolimus at Low Doses in Elderly Kidney Transplant Patients
Status:
Completed
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
There is no consensus on the best immunosuppressive regimen in elderly people. The aim of
this study will be to evaluate the efficacy of sirolimus associated with tacrolimus in
elderly kidney transplant recipients. The investigators will conduct a single-center
prospective randomized study comparing the combination of tacrolimus with sirolimus at
reduced dose rate (tacrolimus + sirolimus group) against tacrolimus with mycophenolate
(tacrolimus + mycophenolate group). The investigators will include all kidney transplant
patients over 60 years of age. The investigators will evaluate estimated glomerular
filtration rate and incidence of cytomegalovirus in 12 month follow-up.