Overview

Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors

Status:
Recruiting
Trial end date:
2024-01-01
Target enrollment:
Participant gender:
Summary
This study aims to determine the efficacy of daily sirolimus and celecoxib, with low dose etoposide alternating with cyclophosphamide for pediatric participants with relapsed or refractory tumors.
Phase:
Phase 2
Details
Lead Sponsor:
Emory University
Collaborators:
Cannonball Kids' Cancer Foundation
Hyundai Hope On Wheels
Treatments:
Celecoxib
Cyclophosphamide
Etoposide
Etoposide phosphate
Everolimus
Sirolimus