Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension
Status:
Recruiting
Trial end date:
2021-09-01
Target enrollment:
Participant gender:
Summary
There is evidence for a high prevalence of Sleep Disorder Breathing (SDB) in patients with
Chronic Thromboembolic Pulmonary Hypertension (CTEPH). Central Sleep Apnea, Cheyne-Stokes
Breathing and Obstructive Sleep Apnea appear to occur in CTEPH. However, there is no
information on the impact of CTEPH treatment modalities on concomitant SDB. Furthermore, the
use of PAP therapy in CTEPH has not yet been investigated. CTEPH is a rare and serious
disease and there may be a bidirectional association of SDB and CTEPH.
This study plans to investigate the prevalence of SDB in CTEPH and compare it to datasets of
large epidemiological studies on SDB. Furthermore, the impact of CTEPH treatment on SDB will
be analyzed and CTEPH patients for possible PAP treatment will be defined.