Sleep Disorders in Chronic Kidney Disease Patients

• Status: Not yet recruiting
• Trial end date: 2024-12-31
• Target enrollment: 0
• Participant gender: All

Summary

1. Asses sleep disorders in CKD patients and those on haemodialysis and related complications ( uncontrolled blood pressure,glomerular filtration rate (GFR) ,proteinuria and psychological disturbance)

2. Asses effect of hypnotics or sedations for 3 month in improvement those complications after taking treatment .

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Assiut University
• Treatments: Quetiapine Fumarate

Criteria

Inclusion Criteria:

• 1.patients are between ages 18 and 60 with chronic kidney disease (CKD)( stage III-V) and ESRD Patients on regular haemodialysis > 6 months.and time of start session of dialysis at 5 pm , thrice weekly .

2. Random urine albumin/creatinine ratio of 30 mcg/day or greater (protein in the urine) 3. Patients have ability to complete a sleep survey and must be able to swallow tablets.

4. Patients with compensated heart and liver disease. 5. Not on antipsychotic drugs.

Exclusion Criteria:

1. Patients with history of psychosis.

2. Patients with decompensated heart or liver disease.

3. Patients with diabetes , autoimmune ,thyroid or neurological disorders.