Slow Stepwise Propofol TCI Induction for Titration Anesthesia Maintenance

• Status: Recruiting
• Trial end date: 2021-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if a slow stepwise propofol TCI induction with Marsh model (Ke0 0.26), allows for an accurate estimation of the effect site concentration required for maintenance of the general anesthesia, with propofol and remifentanil, in adult populations older and younger than 65 years of age.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital Italiano de Buenos Aires
• Treatments: Anesthetics; Propofol; Remifentanil

Criteria

Inclusion Criteria:

• ASA 1 or 2.

• Age over 20 years old.

• Scheduled to undergo elective surgery of minor or medium complexity under general anesthesia.

• Regarding cognitive function: subjects will be considered with enough cognitive function if they are able to read and understand the medical history form by properly answering medical questions during the preoperative anesthesia assessment and being also able to sign the informed consent form.

Exclusion Criteria:

• Pregnancy.

• Obesity (BMI >30).

• Patients taking benzodiazepines or other central nervous system action drugs.

• Subjects with psychiatric disorders with or without treatment.

• Allergies or any adverse reaction to propofol or any of its components (egg lecithin).