Small Volume Simethicone Before Gastroscopy: Any Benefit?

• Status: Completed
• Trial end date: 2015-11-01
• Target enrollment: 0
• Participant gender: All

Summary

A randomized controlled and endoscopist-blinded study which compares the efficacy of liquid simethicone (100mg) in 5 mls water, versus placebo ( 5mls of water), as premedication (given at least 30 minutes) before gastroscopy towards improvement of the total mucosal visibility score.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Changi General Hospital
• Treatments: Simethicone

Criteria

Inclusion Criteria:

• Planned for an elective diagnostic gastroscopy by the attending gastroenterologist

• Age of at least 21 years old

• Mentally competent and able to provide informed consent

Exclusion Criteria:

• Category A patients (incarcerated prisoners)

• adults who are unable to give their own informed consent due to lack of mental capacity

• suspected gastrointestinal bleeding

• suspected impacted foreign material

• suspected gastric outlet obstruction

• suspected esophageal obstruction

• history of dysphagia

• known hypersensitivity to simethicone

• previous gastrectomy