Smooth Extubation With Magnesium Sulphate for General Anesthesia With Endotracheal Intubation

• Status: Completed
• Trial end date: 2021-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Tracheal extubation is a critical event in the anaesthetic management of patients undergoing general anaesthesia with endotracheal intubation for elective procedures. It the state of art to provide suitable conditions for smooth extubation and avoid coughing, bucking, straining and/or laryngospasm. Several methods have been described to provide a smooth extubation, including the use of remifentanil infusion, dexmedetomidine or fentanyl. Because of its anti-inflammatory and analgesic effects and lack of respiratory depressant actions, magnesium sulphate could be an attractive alternative.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fayoum University Hospital
• Treatments: Magnesium Sulfate

Criteria

Inclusion Criteria:

• Elective surgeries that need endotracheal intubation.

• Duration of surgery 1-3 hours

• ASA Ⅰ-Ⅱ

Exclusion Criteria:

• Refusal of patients.

• Patients with hypersensitivity to the study drug.

• Patients with cardiac disorders, bundle branch block, hart block

• Neuromuscular disease, calcium channel blocker medication or hypermagnesemia