Sodium Bicarbonate Versus Saline for the Prevention of Contrast-induced Nephropathy
Status:
Completed
Trial end date:
2006-03-01
Target enrollment:
Participant gender:
Summary
Contrast-induced nephrophaty (CIN) accounts for more than 10% of hospital-acquired renal
failure. Hydration with sodium bicarbonate is more protective than isotonic saline in
animals. Limited data are available in humans. We compared the efficacy of sodium bicarbonate
versus isotonic saline to prevent CIN in a large population of patients with renal
dysfunction undergoing coronary angiography or intervention.