Sodium Citrate 4% Locking Solution for Children Requiring Home Parenteral Nutrition
Status:
Recruiting
Trial end date:
2027-06-01
Target enrollment:
Participant gender:
Summary
This study an open label prospective observational cohort study to evaluate the safety and
efficacy of sodium citrate 4% locking solution in preventing central line associated blood
stream infection in children requiring long term central venous catheters for home parenteral
nutrition. Sodium citrate 4% is FDA-approved for dialysis catheters, but has not been
formally evaluated for use in tunneled catheters for parenteral nutrition. The rate of
central line-associated bloodstream infection (CLABSI) and other potential adverse events
will be monitored for 12 months, with the option to remain in the study for a longer period
of time.