Sodium Fluorescein-Guided Resection of Pediatric Neurosurgical Tumors

• Status: Recruiting
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Sodium fluorescein, which has been shown to be useful for intraoperative guidance regarding the resection of adult neurosurgical tumors, can aid the resection of pediatric neurosurgical tumors.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Colorado, Denver

Criteria

Inclusion Criteria:

• Age 31 days through 21 years on date of surgery

• Undergoing resection of a central nervous system tumor at Children's Hospital Colorado

• Parent/legal guardian (or adult subject) willing and able to complete the informed consent process

Exclusion Criteria:

• Tumor in functionally eloquent cortex that precludes maximal surgical resection

• Severe renal dysfunction

• Preoperative serum creatinine level > than normal range and GFR < 30.

• Severe liver dysfunction

• History of asthma or pulmonary spasm

• Known allergy to sodium fluorescein or any other contrast dye

• Previous administration of sodium fluorescein within the last 72 hours

• Pregnant or nursing mother

• Other unspecified reasons that, in the opinion of the investigator, make the subject unsuitable for enrollment.