Sodium Nitrite in Acute Myocardial Infarction

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether the intravenous infusion of sodium nitrite safely prevents ischemia-reperfusion injury in subjects with acute myocardial infarction resulting in improved left ventricular function.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Johns Hopkins University
• Collaborator: Hope Pharmaceuticals

Criteria

Inclusion Criteria:

• Acute ST segment elevation myocardial infarction

• Eligible for percutaneous coronary intervention

Exclusion Criteria:

• Cardiogenic shock

• Cardiac arrest

• Prior infarct in the infarct related artery

• Hemoglobinopathy, Glucose-6 Phosphate Dehydrogenase (G6PD) deficiency