Overview

Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Status:
Recruiting
Trial end date:
2027-01-01
Target enrollment:
Participant gender:
Summary
This study will attempt to demonstrate the efficacy of Sodium Thiosulfate (STS) in preventing hearing loss in patients re-treated with cisplatin-based therapy according to regimens Cisplatin and STS (regimen CS) and Cisplatin, STS and Vorinostat/SAHA (regimen CSS).
Phase:
Early Phase 1
Details
Lead Sponsor:
Children's Hospital Medical Center, Cincinnati
Treatments:
Cisplatin
Sodium thiosulfate
Vorinostat